Clinical trial of deglycyrrhizinised liquorice in gastric ulcer.

نویسندگان

  • K D Bardhan
  • D C Cumberland
  • R A Dixon
  • C D Holdsworth
چکیده

Ninety-six patients with gastric ulcer were randomly allocated to treatment either with deglycyrrhizinised liquorice or placebo. After four weeks no differences were found between the treatment groups in the proportions with complete healing, whether assessed by gastroscopy or radiology, or in the percentage reduction in ulcer area, or in clinical improvement.

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منابع مشابه

Double-blind trial of deglycyrrhizinated liquorice in gastric ulcer.

In order to investigate further the reported beneficial effect of deglycyrrhizinated liquorice in gastric ulcer, a trial with a double-blind, cross-over design was performed. The patients were treated during two consecutive periods of four weeks each with either liquorice extract during the first period and placebo during the second or placebo during the first period and liquorice during the se...

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Clinical trial of deglycyrrhizinized liquorice in gastric ulcer.

In the past twenty years evidence has accumulated that liquorice and related compounds accelerate the rate of healing of gastric ulcers. Powdered succus liquiritiae (Revers, 1948) and glycyrrhiza extract (Schulze, Franke, and Keller, 1954; Ferenbach, 1954; Ohrt, 1955) were shown to be beneficial in patients with gastric ulcer but adequately controlled clinical trials of liquorice extracts were ...

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Some experience with deglycyrrhizinated liquorice in the treatment of gastric and duodenal ulcers with special reference to its spasmolytic effect.

Liquorice has been used in medicine for many years, originally as a sweetening agent, but its efficacy was not fully realized until Revers (1946, 1958) found that peptic ulcers healed rapidly with its extract. However, oedema, heartburn, congestive cardiac failure, and headaches were commonly encountered as side effects of the crude extract. Molhuysen, Gerbrandy, de Vries, de Jong, Renstia, Tur...

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عنوان ژورنال:
  • Gut

دوره 19 9  شماره 

صفحات  -

تاریخ انتشار 1978